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Proteins/UNIPROT:Q08357
Sodium-phosphate symporter which preferentially transports the monovalent form of phosphate with a stoichiometry of two sodium ions per phosphate ion. Plays a critical role in the determination of bone quality and strength by providing phosphate for bone mineralization (By similarity). Required to maintain normal cerebrospinal fluid phosphate levels (By similarity). Mediates phosphate-induced calcification of vascular smooth muscle cells (VCMCs) and can functionally compensate for loss of SLC20A1 in VCMCs (By similarity)..
(Microbial infection) Functions as a retroviral receptor and confers human cells susceptibility to infection to amphotropic murine leukemia virus (A-MuLV), 10A1 murine leukemia virus (10A1 MLV) and some feline leukemia virus subgroup B (FeLV-B) variants..
Function from UniProtKB (Q08357), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
1 statement
1 statement · 1 reference database · Subject: SLC20A2 · Sources: Hetionet
3 reactions
3sodium(1+)+phosphate(3-)3sodium(1+)+phosphate(3-)
Transported by SLC17A2 or SLC17A3 or SLC17A1 or SLC34A1 or SLC17A4 or SLC20A1 or SLC20A2
Reaction pageLeft to rightBalancedGO:0005615, GO:0005829
Human-GEM MAR04910CC BY 4.0Reference data
8 names
Resolves to: SLC20A2
Reaction pageLeft to rightBalancedGO:0005615, GO:0005829
Human-GEM MAR04912CC BY 4.0Reference data
2sodium(1+)+hydrogenphosphate2sodium(1+)+hydrogenphosphate
Transported by SLC20A2 or SLC34A3 or SLC20A1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:71259CC BY 4.0Reference data