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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:P81133

SIM1

Protein·UNIPROT:P81133

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Transcriptional factor that may have pleiotropic effects during embryogenesis and in the adult.

Function from UniProtKB (P81133), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

3 rows

complex neurodevelopmental disorder has a germline basis in SIM1DiseaseGenCC HGNC:10882|MONDO:0100038Inferred only
inherited obesity has a germline basis in SIM1DiseaseGenCC HGNC:10882|MONDO:0019182Inferred only
obesity due to SIM1 deficiency has a germline basis in SIM1DiseaseGenCC HGNC:10882|MONDO:0018244Inferred only

Statements

2 statements

2 statements · 2 reference databases · Subject: SIM1 · Sources: gene ontology, Hetionet

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HSP90AA1 interacts with SIM1ProteinHetionet hetionet:interacts:3320-6492Inferred only
SIM1 regulates regulation of transcription by RNA polymerase IIBiological processgene ontology P81133|GO:0006357Inferred only

Other names

2 names

Resolves to: SIM1

Also called: BHLHE14Class E basic helix-loop-helix protein 14

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