Proteins/UNIPROT:O15389

SIGLEC5

ProteinUNIPROT:O15389

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

Function from UniProtKB (O15389), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

9 statements

9 statements · 2 reference databases · Subject: SIGLEC5 · Sources: Hetionet, Reactome

Order

GCGR covaries with SIGLEC5ProteinHetionet hetionet:covaries:2642-8778Inferred only
PCCB covaries with SIGLEC5ProteinHetionet hetionet:covaries:5096-8778Inferred only
SH3PXD2B covaries with SIGLEC5ProteinHetionet hetionet:covaries:285590-8778Inferred only
SIGLEC5 interacts with TRIP13ProteinHetionet hetionet:interacts:8778-9319Inferred only
SIGLEC5 participates in Adaptive Immune SystemPathwayReactome R-HSA-1280218Inferred only
SIGLEC5 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
SIGLEC5 participates in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellPathwayReactome R-HSA-198933Inferred only
SIGLEC5 participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only
SIGLEC5 participates in Neutrophil degranulationPathwayReactome R-HSA-6798695Inferred only

Other names

8 names

Resolves to: SIGLEC5

Also called: CD antigen CD170CD33 antigen-like 2CD33L2OB-binding protein 2OB-BP2OBBP2Obesity-binding protein 2Siglec-5

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