Proteins/UNIPROT:Q6PI26

SHQ1

ProteinUNIPROT:Q6PI26

Required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs), including telomerase, probably through the stabilization of DKC1, from the time of its synthesis until its association with NOP10, NHP2, and NAF1 at the nascent H/ACA RNA..

Function from UniProtKB (Q6PI26), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

neurodevelopmental disorder with dystonia and seizures has a germline basis in SHQ1DiseaseGenCC HGNC:25543|MONDO:0859258Inferred only

Statements

12 statements

12 statements · 2 reference databases · Subject: SHQ1 · Sources: Hetionet, Reactome

Order

SHQ1 covaries with CFAP161ProteinHetionet hetionet:covaries:161502-55164Inferred only
RGS22 covaries with SHQ1ProteinHetionet hetionet:covaries:26166-55164Inferred only
TRIM52 covaries with SHQ1ProteinHetionet hetionet:covaries:55164-84851Inferred only
DKC1 interacts with SHQ1ProteinHetionet hetionet:interacts:1736-55164Inferred only
SHQ1 interacts with NAF1ProteinHetionet hetionet:interacts:55164-92345Inferred only
UBC interacts with SHQ1ProteinHetionet hetionet:interacts:55164-7316Inferred only
SHQ1 participates in Cell CyclePathwayReactome R-HSA-1640170Inferred only
SHQ1 participates in Chromosome MaintenancePathwayReactome R-HSA-73886Inferred only
SHQ1 participates in Extension of TelomeresPathwayReactome R-HSA-180786Inferred only
SHQ1 participates in Telomere Extension By TelomerasePathwayReactome R-HSA-171319Inferred only
SHQ1 participates in Telomere MaintenancePathwayReactome R-HSA-157579Inferred only
GATA3 decreases the expression of SHQ1ProteinHetionet hetionet:regulates:2625-55164Inferred only

Other names

2 names

Resolves to: SHQ1

Also called: Protein SHQ1 homologSHQ1 homolog

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