Proteins/UNIPROT:Q14141

SEPTIN6

ProteinUNIPROT:Q14141

Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation..

Function from UniProtKB (Q14141), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

16 statements

16 statements · 2 reference databases · Subject: SEPTIN6 · Sources: Hetionet, WikiPathways

Order

ADGRD2 covaries with SEPTIN6ProteinHetionet hetionet:covaries:23157-347088Inferred only
SEPTIN6 covaries with RAB1BProteinHetionet hetionet:covaries:23157-81876Inferred only
CDC42EP2 interacts with SEPTIN6ProteinHetionet hetionet:interacts:10435-23157Inferred only
CDC42EP3 interacts with SEPTIN6ProteinHetionet hetionet:interacts:10602-23157Inferred only
CFTR interacts with SEPTIN6ProteinHetionet hetionet:interacts:1080-23157Inferred only
S100A4 interacts with SEPTIN6ProteinHetionet hetionet:interacts:23157-6275Inferred only
SEPTIN1 interacts with SEPTIN6ProteinHetionet hetionet:interacts:1731-23157Inferred only
SEPTIN6 interacts with SEPTIN12ProteinHetionet hetionet:interacts:124404-23157Inferred only
SEPTIN2 interacts with SEPTIN6ProteinHetionet hetionet:interacts:23157-4735Inferred only
SEPTIN5 interacts with SEPTIN6ProteinHetionet hetionet:interacts:23157-5413Inferred only
SEPTIN9 interacts with SEPTIN6ProteinHetionet hetionet:interacts:10801-23157Inferred only
SEPTIN6 interacts with SOCS7ProteinHetionet hetionet:interacts:23157-30837Inferred only

Show the remaining 4

SUMO1 interacts with SEPTIN6ProteinHetionet hetionet:interacts:23157-7341Inferred only
TK1 interacts with SEPTIN6ProteinHetionet hetionet:interacts:23157-7083Inferred only
UBC interacts with SEPTIN6ProteinHetionet hetionet:interacts:23157-7316Inferred only
SEPTIN6 participates in 2q37 copy number variation syndromePathwayWikiPathways WP5224Inferred only

Other names

4 names

Resolves to: SEPTIN6

Also called: KIAA0128SEP2SEPT6Septin-6

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