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Proteins/UNIPROT:Q15283

RASA2

Protein·UNIPROT:Q15283

Open in the graph

Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4).

Function from UniProtKB (Q15283), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

1 row

Noonan syndrome has a germline basis in RASA2DiseaseGenCC HGNC:9872|MONDO:0018997Inferred only

Statements

13 statements

13 statements · 4 reference databases · Subject: RASA2 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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GNA12 interacts with RASA2ProteinHetionet hetionet:interacts:2768-5922Inferred only
RASA2 interacts with UBCProteinHetionet hetionet:interacts:5922-7316Inferred only
RASA2 participates in Ebola virus infection in hostPathwayWikiPathways WP4217Inferred only
RASA2 participates in MAPK family signaling cascadesPathwayReactome R-HSA-5683057Inferred only
RASA2 participates in MAPK signalingPathwayWikiPathways WP382Inferred only
RASA2 participates in MAPK1/MAPK3 signalingPathwayReactome R-HSA-5684996Inferred only
RASA2 participates in Modulators of TCR signaling and T cell activationPathwayWikiPathways WP5072Inferred only
RASA2 participates in RAF/MAP kinase cascadePathwayReactome R-HSA-5673001Inferred only
RASA2 participates in Ras signalingPathwayWikiPathways WP4223Inferred only
RASA2 participates in Regulation of RAS by GAPsPathwayReactome R-HSA-5658442Inferred only
RASA2 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
RASA2 regulates negative regulation of Ras protein signal transductionBiological processgene ontology Q15283|GO:0046580Inferred only

Show the remaining 1

RASA2 regulates regulation of intracellular signal transductionBiological processgene ontology Q15283|GO:1902531Inferred only

Other names

3 names

Resolves to: RASA2

Also called: GAP1MGTPase-activating protein 1mRASGAP

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