Proteins/UNIPROT:Q9BTL3

RAMAC

ProteinUNIPROT:Q9BTL3

Regulatory subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Promotes the recruitment of the methyl donor, S-adenosyl-L-methionine, to RNMT. Regulates RNMT expression by a post-transcriptional stabilizing mechanism. Binds RNA..

Function from UniProtKB (Q9BTL3), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

15 statements

15 statements · 3 reference databases · Subject: RAMAC · Sources: Hetionet, Reactome, WikiPathways

Order

DBN1 covaries with RAMACProteinHetionet hetionet:covaries:1627-83640Inferred only
CAND1 interacts with RAMACProteinHetionet hetionet:interacts:55832-83640Inferred only
COPS5 interacts with RAMACProteinHetionet hetionet:interacts:10987-83640Inferred only
CUL2 interacts with RAMACProteinHetionet hetionet:interacts:83640-8453Inferred only
CUL3 interacts with RAMACProteinHetionet hetionet:interacts:83640-8452Inferred only
PLSCR1 interacts with RAMACProteinHetionet hetionet:interacts:5359-83640Inferred only
RBMX interacts with RAMACProteinHetionet hetionet:interacts:27316-83640Inferred only
RBPMS interacts with RAMACProteinHetionet hetionet:interacts:11030-83640Inferred only
RAMAC interacts with RHOXF2ProteinHetionet hetionet:interacts:83640-84528Inferred only
RAMAC participates in 15q25 copy number variationPathwayWikiPathways WP5408Inferred only
RAMAC participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
RAMAC participates in Metabolism of RNAPathwayReactome R-HSA-8953854Inferred only

Show the remaining 3

RAMAC participates in mRNA CappingPathwayReactome R-HSA-72086Inferred only
RAMAC participates in RNA Pol II CTD phosphorylation and interaction with CEPathwayReactome R-HSA-77075Inferred only
RAMAC participates in RNA Polymerase II TranscriptionPathwayReactome R-HSA-73857Inferred only

Other names

8 names

Resolves to: RAMAC

Also called: C15orf18FAM103A1Protein FAM103A1RAMRAMMETRNA guanine-7 methyltransferase activating subunitRNMT-activating mini proteinRNMT-activating mRNA cap methyltransferase subunit

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