Proteins/UNIPROT:Q2KHR3

QSER1

ProteinUNIPROT:Q2KHR3

Plays an essential role in the protection and maintenance of transcriptional and developmental programs. Protects many bivalent promoters and poised enhancers from hypermethylation, showing a marked preference for these regulatory elements over other types of promoters or enhancers. Mechanistically, cooperates with TET1 and binds to DNA in a common complex to inhibit the binding of DNMT3A/3B and therefore de novo methylation..

Function from UniProtKB (Q2KHR3), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

9 statements

9 statements · 1 reference database · Subject: QSER1 · Sources: Hetionet

Order

INSM2 covaries with QSER1ProteinHetionet hetionet:covaries:79832-84684Inferred only
JAK3 covaries with QSER1ProteinHetionet hetionet:covaries:3718-79832Inferred only
QSER1 covaries with JMJD1CProteinHetionet hetionet:covaries:221037-79832Inferred only
KIFC1 covaries with QSER1ProteinHetionet hetionet:covaries:3833-79832Inferred only
OXNAD1 covaries with QSER1ProteinHetionet hetionet:covaries:79832-92106Inferred only
QSER1 covaries with PIGVProteinHetionet hetionet:covaries:55650-79832Inferred only
QSER1 covaries with ZNF644ProteinHetionet hetionet:covaries:79832-84146Inferred only
SUMO2 interacts with QSER1ProteinHetionet hetionet:interacts:6613-79832Inferred only
UBC interacts with QSER1ProteinHetionet hetionet:interacts:7316-79832Inferred only

Other names

1 name

Resolves to: QSER1

Also called: Glutamine and serine-rich protein 1

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