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Proteins/UNIPROT:P04553

PRM1

Protein·UNIPROT:P04553

Open in the graph

Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.

Function from UniProtKB (P04553), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

6 statements

6 statements · 3 reference databases · Subject: PRM1 · Sources: Hetionet, Reactome, WikiPathways

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LBR interacts with PRM1ProteinHetionet hetionet:interacts:3930-5619Inferred only
PRM1 interacts with SRPK1ProteinHetionet hetionet:interacts:5619-6732Inferred only
PRM1 participates in Developmental BiologyPathwayReactome R-HSA-1266738Inferred only
PRM1 participates in Male infertilityPathwayWikiPathways WP4673Inferred only
PRM1 participates in Maternal to zygotic transition (MZT)PathwayReactome R-HSA-9816359Inferred only
PRM1 participates in Replacement of protamines by nucleosomes in the male pronucleusPathwayReactome R-HSA-9821993Inferred only

Other names

2 names

Resolves to: PRM1

Also called: Cysteine-rich protamineSperm protamine P1

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