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Proteins/UNIPROT:Q7Z3G6
Is involved in the organization and maintenance of axon initial segment (AIS) architecture, likely cooperating with IGSF9B to regulate ANK3/ANKG localization to AIS (By similarity). By binding to and regulating ANK3/ANKG, it modulates its ability to bundle microtubules, a crucial mechanism for establishing neuronal polarity and AIS formation (By similarity). During early embryonic development, has a role in blastocyst formation, likely controlling the redistribution of the microtubule network during embryo compaction and the establishment of apical/basal cell polarity (By similarity)..
Function from UniProtKB (Q7Z3G6), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
6 statements
6 statements · 2 reference databases · Subject: PRICKLE2 · Sources: Hetionet, WikiPathways
1 name
Resolves to: PRICKLE2