Loading the page.
Proteins/UNIPROT:Q9H4Q4
Transcriptional regulator necessary for the development of nociceptive neurons, playing a key role in determining the nociceptive lineage from neural crest cell progenitors. Initiates neurogenesis and activates downstream pro-neuronal transcription factors, such as NEUROD1, BRN3A, and ISL1, specifically within nociceptive neurons, while repressing non-nociceptor cell fates. Essential for the proper function of nociceptors in adults, influencing both their excitability and their gene expression, thereby impacting how these neurons respond to various pain stimuli..
Function from UniProtKB (Q9H4Q4), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
8 statements
8 statements · 2 reference databases · Subject: PRDM12 · Sources: gene ontology, Hetionet
3 names
Resolves to: PRDM12