Proteins/UNIPROT:Q9BY77

POLDIP3

ProteinUNIPROT:Q9BY77

Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by association with the TREX complex..

Function from UniProtKB (Q9BY77), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

17 statements

17 statements · 3 reference databases · Subject: POLDIP3 · Sources: gene ontology, Hetionet, Reactome

Order

POLDIP3 covaries with MAN1C1ProteinHetionet hetionet:covaries:57134-84271Inferred only
VPS37D covaries with POLDIP3ProteinHetionet hetionet:covaries:155382-84271Inferred only
ZNF300 covaries with POLDIP3ProteinHetionet hetionet:covaries:84271-91975Inferred only
ERH interacts with POLDIP3ProteinHetionet hetionet:interacts:2079-84271Inferred only
HDGF interacts with POLDIP3ProteinHetionet hetionet:interacts:3068-84271Inferred only
NCBP1 interacts with POLDIP3ProteinHetionet hetionet:interacts:4686-84271Inferred only
POLD2 interacts with POLDIP3ProteinHetionet hetionet:interacts:5425-84271Inferred only
RPS6KB1 interacts with POLDIP3ProteinHetionet hetionet:interacts:6198-84271Inferred only
SIRT7 interacts with POLDIP3ProteinHetionet hetionet:interacts:51547-84271Inferred only
TERF2 interacts with POLDIP3ProteinHetionet hetionet:interacts:7014-84271Inferred only
UBC interacts with POLDIP3ProteinHetionet hetionet:interacts:7316-84271Inferred only
POLDIP3 participates in Metabolism of RNAPathwayReactome R-HSA-8953854Inferred only

Show the remaining 5

POLDIP3 participates in mRNA 3'-end processingPathwayReactome R-HSA-72187Inferred only
POLDIP3 participates in Processing of Capped Intron-Containing Pre-mRNAPathwayReactome R-HSA-72203Inferred only
POLDIP3 participates in Transport of Mature mRNA derived from an Intron-Containing TranscriptPathwayReactome R-HSA-159236Inferred only
POLDIP3 participates in Transport of Mature Transcript to CytoplasmPathwayReactome R-HSA-72202Inferred only
POLDIP3 regulates positive regulation of translationBiological processgene ontology Q9BY77|GO:0045727Inferred only

Other names

6 names

Resolves to: POLDIP3

Also called: 46 kDa DNA polymerase delta interaction proteinKIAA1649p46PDIP46S6K1 Aly/REF-like targetSKAR

← Every protein Find it in the graph →