Proteins/UNIPROT:Q9GZP4

PITHD1

ProteinUNIPROT:Q9GZP4

Promotes megakaryocyte differentiation by up-regulating RUNX1 expression. Regulates RUNX1 expression by activating the proximal promoter of the RUNX1 gene and by enhancing the translation activity of an internal ribosome entry site (IRES) element in the RUNX1 gene..

Function from UniProtKB (Q9GZP4), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

16 statements

16 statements · 2 reference databases · Subject: PITHD1 · Sources: gene ontology, Hetionet

Order

ARF5 covaries with PITHD1ProteinHetionet hetionet:covaries:381-57095Inferred only
BRSK1 covaries with PITHD1ProteinHetionet hetionet:covaries:57095-84446Inferred only
DNASE1L1 covaries with PITHD1ProteinHetionet hetionet:covaries:1774-57095Inferred only
GPR137 covaries with PITHD1ProteinHetionet hetionet:covaries:56834-57095Inferred only
JPT1 covaries with PITHD1ProteinHetionet hetionet:covaries:51155-57095Inferred only
KLHL5 covaries with PITHD1ProteinHetionet hetionet:covaries:51088-57095Inferred only
NDN covaries with PITHD1ProteinHetionet hetionet:covaries:4692-57095Inferred only
PTPN6 covaries with PITHD1ProteinHetionet hetionet:covaries:57095-5777Inferred only
SNRPN covaries with PITHD1ProteinHetionet hetionet:covaries:57095-6638Inferred only
SYT5 covaries with PITHD1ProteinHetionet hetionet:covaries:57095-6861Inferred only
THAP12 covaries with PITHD1ProteinHetionet hetionet:covaries:5612-57095Inferred only
PITHD1 interacts with CDC73ProteinHetionet hetionet:interacts:57095-79577Inferred only

Show the remaining 4

PITHD1 interacts with SUMO4ProteinHetionet hetionet:interacts:387082-57095Inferred only
UBC interacts with PITHD1ProteinHetionet hetionet:interacts:57095-7316Inferred only
PITHD1 regulates positive regulation of DNA-templated transcriptionBiological processgene ontology Q9GZP4|GO:0045893Inferred only
PITHD1 regulates positive regulation of megakaryocyte differentiationBiological processgene ontology Q9GZP4|GO:0045654Inferred only

Other names

2 names

Resolves to: PITHD1

Also called: C1orf128PITH domain-containing protein 1

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