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Proteins/UNIPROT:Q96LB8

PGLYRP4

Protein·UNIPROT:Q96LB8

Open in the graph

Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Also binds to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity..

Function from UniProtKB (Q96LB8), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

4 statements

4 statements · 2 reference databases · Subject: PGLYRP4 · Sources: Human-GEM, Reactome

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PGLYRP4 participates in Antimicrobial peptidesPathwayReactome R-HSA-6803157Inferred only
PGLYRP4 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
PGLYRP4 participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only
N-acetyl-alpha-D-muramoyl-L-alanine is a substrate of PGLYRP4CompoundHuman-GEM MAR09529Inferred only

Reactions

1 reaction

water+N-acetyl-alpha-D-muramoyl-L-alanineL-alanine+N-acetyl-D-muramic acid
Catalysed by PGLYRP1 or PGLYRP3 or PGLYRP2 or PGLYRP4
Reaction pageLeft to rightBalancedEC 3.5.1.28cytosol
Human-GEM MAR09529CC BY 4.0Reference data

Other names

5 names

Resolves to: PGLYRP4

Also called: Peptidoglycan recognition protein I-betaPeptidoglycan recognition protein intermediate betaPGLYRPIbetaPGRP-I-betaPGRPIB

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