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Proteins/UNIPROT:P20774

OGN

Protein·UNIPROT:P20774

Open in the graph

Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2..

Function from UniProtKB (P20774), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

18 statements

18 statements · 3 reference databases · Subject: OGN · Sources: gene ontology, Hetionet, Reactome

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ABL1 interacts with OGNProteinHetionet hetionet:interacts:25-4969Inferred only
CRK interacts with OGNProteinHetionet hetionet:interacts:1398-4969Inferred only
IRF1 interacts with OGNProteinHetionet hetionet:interacts:3659-4969Inferred only
OGN interacts with SRCProteinHetionet hetionet:interacts:4969-6714Inferred only
OGN participates in Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)PathwayReactome R-HSA-3656244Inferred only
OGN participates in Defective CHST6 causes MCDC1PathwayReactome R-HSA-3656225Inferred only
OGN participates in Defective ST3GAL3 causes MCT12 and EIEE15PathwayReactome R-HSA-3656243Inferred only
OGN participates in DiseasePathwayReactome R-HSA-1643685Inferred only
OGN participates in Diseases associated with glycosaminoglycan metabolismPathwayReactome R-HSA-3560782Inferred only
OGN participates in Diseases of glycosylationPathwayReactome R-HSA-3781865Inferred only
OGN participates in Diseases of metabolismPathwayReactome R-HSA-5668914Inferred only
OGN participates in Glycosaminoglycan metabolismPathwayReactome R-HSA-1630316Inferred only

Show the remaining 6

OGN participates in Keratan sulfate biosynthesisPathwayReactome R-HSA-2022854Inferred only
OGN participates in Keratan sulfate degradationPathwayReactome R-HSA-2022857Inferred only
OGN participates in Keratan sulfate/keratin metabolismPathwayReactome R-HSA-1638074Inferred only
OGN participates in MetabolismPathwayReactome R-HSA-1430728Inferred only
OGN participates in Metabolism of carbohydrates and carbohydrate derivativesPathwayReactome R-HSA-71387Inferred only
OGN regulates negative regulation of smooth muscle cell proliferationBiological processgene ontology P20774|GO:0048662Inferred only

Other names

4 names

Resolves to: OGN

Also called: OIFOsteoglycinOsteoinductive factorSLRR3A

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