Proteins/UNIPROT:Q92886

NEUROG1

ProteinUNIPROT:Q92886

Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity)..

Function from UniProtKB (Q92886), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

cranial dysinnervation disorder, congenital, with absent corneal reflex and developmental delay has a germline basis in NEUROG1DiseaseGenCC HGNC:7764|MONDO:0957563Inferred only

Statements

29 statements

29 statements · 3 reference databases · Subject: NEUROG1 · Sources: gene ontology, Hetionet, WikiPathways

Order

NEUROG1 covaries with CARMIL2ProteinHetionet hetionet:covaries:146206-4762Inferred only
NEUROG1 covaries with CBFA2T2ProteinHetionet hetionet:covaries:4762-9139Inferred only
NEUROG1 covaries with CNTN1ProteinHetionet hetionet:covaries:1272-4762Inferred only
CXXC5 covaries with NEUROG1ProteinHetionet hetionet:covaries:4762-51523Inferred only
NEUROG1 covaries with FAM227BProteinHetionet hetionet:covaries:196951-4762Inferred only
NEUROG1 covaries with GAL3ST3ProteinHetionet hetionet:covaries:4762-89792Inferred only
NEUROG1 covaries with IRX1ProteinHetionet hetionet:covaries:4762-79192Inferred only
MLF2 covaries with NEUROG1ProteinHetionet hetionet:covaries:4762-8079Inferred only
NEUROG1 covaries with NECAB3ProteinHetionet hetionet:covaries:4762-63941Inferred only
OR6P1 covaries with NEUROG1ProteinHetionet hetionet:covaries:128366-4762Inferred only
NEUROG1 covaries with SLC22A17ProteinHetionet hetionet:covaries:4762-51310Inferred only
NEUROG1 covaries with SNAI1ProteinHetionet hetionet:covaries:4762-6615Inferred only

Show the remaining 17

NEUROG1 covaries with SRCProteinHetionet hetionet:covaries:4762-6714Inferred only
NEUROG1 covaries with THAP7ProteinHetionet hetionet:covaries:4762-80764Inferred only
TIPARP covaries with NEUROG1ProteinHetionet hetionet:covaries:25976-4762Inferred only
TMEM178B covaries with NEUROG1ProteinHetionet hetionet:covaries:100507421-4762Inferred only
NEUROG1 interacts with CBFA2T2ProteinHetionet hetionet:interacts:4762-9139Inferred only
CREBBP interacts with NEUROG1ProteinHetionet hetionet:interacts:1387-4762Inferred only
RUNX1T1 interacts with NEUROG1ProteinHetionet hetionet:interacts:4762-862Inferred only
SMAD1 interacts with NEUROG1ProteinHetionet hetionet:interacts:4086-4762Inferred only
NEUROG1 interacts with TARBP2ProteinHetionet hetionet:interacts:4762-6895Inferred only
NEUROG1 participates in Kallmann syndromePathwayWikiPathways WP5074Inferred only
NEUROG1 participates in Neural crest differentiationPathwayWikiPathways WP2064Inferred only
NEUROG1 regulates negative regulation of relaxation of muscleBiological processgene ontology Q92886|GO:1901078Inferred only
NEUROG1 regulates negative regulation of saliva secretionBiological processgene ontology Q92886|GO:1905747Inferred only
NEUROG1 regulates positive regulation of neuron differentiationBiological processgene ontology Q92886|GO:0045666Inferred only
NEUROG1 regulates positive regulation of transcription by RNA polymerase IIBiological processgene ontology Q92886|GO:0045944Inferred only
NEUROG1 regulates regulation of muscle organ developmentBiological processgene ontology Q92886|GO:0048634Inferred only
NEUROG1 regulates regulation of transcription by RNA polymerase IIBiological processgene ontology Q92886|GO:0006357Inferred only

Other names

8 names

Resolves to: NEUROG1

Also called: BHLHA6Class A basic helix-loop-helix protein 6NEUROD3Neurogenic basic-helix-loop-helix proteinNeurogenic differentiation factor 3NGNNGN-1NGN1

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