Proteins/UNIPROT:Q8IXM3

MRPL41

ProteinUNIPROT:Q8IXM3

Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins..

Function from UniProtKB (Q8IXM3), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

12 statements

12 statements · 2 reference databases · Subject: MRPL41 · Sources: Hetionet, Reactome

Order

CAND1 interacts with MRPL41ProteinHetionet hetionet:interacts:55832-64975Inferred only
MRPL58 interacts with MRPL41ProteinHetionet hetionet:interacts:3396-64975Inferred only
SMURF2 interacts with MRPL41ProteinHetionet hetionet:interacts:64750-64975Inferred only
MRPL41 interacts with TRIM63ProteinHetionet hetionet:interacts:64975-84676Inferred only
UBC interacts with MRPL41ProteinHetionet hetionet:interacts:64975-7316Inferred only
MRPL41 participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
MRPL41 participates in Mitochondrial ribosome-associated quality controlPathwayReactome R-HSA-9937383Inferred only
MRPL41 participates in Mitochondrial translationPathwayReactome R-HSA-5368287Inferred only
MRPL41 participates in Mitochondrial translation elongationPathwayReactome R-HSA-5389840Inferred only
MRPL41 participates in Mitochondrial translation initiationPathwayReactome R-HSA-5368286Inferred only
MRPL41 participates in Mitochondrial translation terminationPathwayReactome R-HSA-5419276Inferred only
MRPL41 participates in TranslationPathwayReactome R-HSA-72766Inferred only

Other names

9 names

Resolves to: MRPL41

Also called: 39S ribosomal protein L41, mitochondrialBcl-2-interacting mitochondrial ribosomal protein L41BMRPCell proliferation-inducing gene 3 proteinL41mtMRP-L27 homologMRP-L41MRPL27RPML27

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