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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:P22897

MRC1

Protein·UNIPROT:P22897

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Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.

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(Microbial infection) Acts as a phagocytic receptor for bacteria, fungi and other pathogens.

(Microbial infection) Acts as a receptor for Dengue virus envelope protein E..

(Microbial infection) Interacts with Hepatitis B virus envelope protein..

Function from UniProtKB (P22897), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

18 statements

18 statements · 3 reference databases · Subject: MRC1 · Sources: Hetionet, Reactome, WikiPathways

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PHOSPHO1 covaries with MRC1ProteinHetionet hetionet:covaries:162466-4360Inferred only
SLC35B2 covaries with MRC1ProteinHetionet hetionet:covaries:347734-4360Inferred only
MRC1 interacts with CHEK2ProteinHetionet hetionet:interacts:11200-4360Inferred only
MRC1 interacts with UBCProteinHetionet hetionet:interacts:4360-7316Inferred only
MRC1 participates in Adaptive Immune SystemPathwayReactome R-HSA-1280218Inferred only
MRC1 participates in Antigen processing-Cross presentationPathwayReactome R-HSA-1236975Inferred only
MRC1 participates in Bacterial Infection PathwaysPathwayReactome R-HSA-9824439Inferred only
MRC1 participates in Class I MHC mediated antigen processing & presentationPathwayReactome R-HSA-983169Inferred only
MRC1 participates in Cross-presentation of soluble exogenous antigens (endosomes)PathwayReactome R-HSA-1236978Inferred only
MRC1 participates in Dengue Virus Attachment and EntryPathwayReactome R-HSA-9918485Inferred only
MRC1 participates in Dengue Virus InfectionPathwayReactome R-HSA-9839923Inferred only
MRC1 participates in DiseasePathwayReactome R-HSA-1643685Inferred only

Show the remaining 6

MRC1 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
MRC1 participates in Infection with Mycobacterium tuberculosisPathwayReactome R-HSA-9635486Inferred only
MRC1 participates in Infectious diseasePathwayReactome R-HSA-5663205Inferred only
MRC1 participates in Modulation by Mtb of host immune systemPathwayReactome R-HSA-9637628Inferred only
MRC1 participates in Uterine natural killer cells and progesterone estrogen and chorionic gonadotropinPathwayWikiPathways WP5569Inferred only
MRC1 participates in Viral Infection PathwaysPathwayReactome R-HSA-9824446Inferred only

Other names

10 names

Resolves to: MRC1

Also called: C-type lectin domain family 13 member DC-type lectin domain family 13 member D-likeCD antigen CD206CLEC13DCLEC13DLhMRHuman mannose receptorMacrophage mannose receptor 1-like protein 1MMRMRC1L1

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