Proteins/UNIPROT:Q13361

MFAP5

ProteinUNIPROT:Q13361

May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity (By similarity). Component of the elastin-associated microfibrils..

Function from UniProtKB (Q13361), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

aortic aneurysm, familial thoracic 9 has a germline basis in MFAP5DiseaseGenCC HGNC:29673|MONDO:0014514Inferred only
familial thoracic aortic aneurysm and aortic dissection has a germline basis in MFAP5DiseaseGenCC HGNC:29673|MONDO:0019625Inferred only

Statements

14 statements

14 statements · 3 reference databases · Subject: MFAP5 · Sources: Hetionet, Reactome, WikiPathways

Order

FBLN1 interacts with MFAP5ProteinHetionet hetionet:interacts:2192-8076Inferred only
FBN2 interacts with MFAP5ProteinHetionet hetionet:interacts:2201-8076Inferred only
MEGF6 interacts with MFAP5ProteinHetionet hetionet:interacts:1953-8076Inferred only
MFAP5 participates in Elastic fibre formationPathwayReactome R-HSA-1566948Inferred only
MFAP5 participates in Extracellular matrix organizationPathwayReactome R-HSA-1474244Inferred only
MFAP5 participates in MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangementPathwayWikiPathways WP4560Inferred only
MFAP5 participates in MFAP5 mediated ovarian cancer cell motility and invasivenessPathwayWikiPathways WP3301Inferred only
MFAP5 participates in Molecules associated with elastic fibresPathwayReactome R-HSA-2129379Inferred only
ACAT2 increases the expression of MFAP5ProteinHetionet hetionet:regulates:39-8076Inferred only
BRAF increases the expression of MFAP5ProteinHetionet hetionet:regulates:673-8076Inferred only
DRAP1 decreases the expression of MFAP5ProteinHetionet hetionet:regulates:10589-8076Inferred only
MOK increases the expression of MFAP5ProteinHetionet hetionet:regulates:5891-8076Inferred only

Show the remaining 2

TGDS increases the expression of MFAP5ProteinHetionet hetionet:regulates:23483-8076Inferred only
TIMP2 decreases the expression of MFAP5ProteinHetionet hetionet:regulates:7077-8076Inferred only

Other names

5 names

Resolves to: MFAP5

Also called: MAGP-2MAGP2MFAP-5Microfibril-associated glycoprotein 2MP25

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