Proteins/UNIPROT:O95711

LY86

ProteinUNIPROT:O95711

May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression (By similarity)..

Function from UniProtKB (O95711), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

9 statements

9 statements · 3 reference databases · Subject: LY86 · Sources: gene ontology, Hetionet, Reactome

Order

APP interacts with LY86ProteinHetionet hetionet:interacts:351-9450Inferred only
CD180 interacts with LY86ProteinHetionet hetionet:interacts:4064-9450Inferred only
IRF8 interacts with LY86ProteinHetionet hetionet:interacts:3394-9450Inferred only
LY86 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
LY86 participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only
LY86 participates in Toll Like Receptor 4 (TLR4) CascadePathwayReactome R-HSA-166016Inferred only
LY86 participates in Toll-like Receptor CascadesPathwayReactome R-HSA-168898Inferred only
LY86 regulates positive regulation of lipopolysaccharide-mediated signaling pathwayBiological processgene ontology O95711|GO:0031666Inferred only
TIMM9 decreases the expression of LY86ProteinHetionet hetionet:regulates:26520-9450Inferred only

Other names

4 names

Resolves to: LY86

Also called: Ly-86MD-1MD1Protein MD-1

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