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Proteins/UNIPROT:Q15722

LTB4R

Protein·UNIPROT:Q15722

Open in the graph

Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.

Function from UniProtKB (Q15722), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

16 statements

16 statements · 3 reference databases · Subject: LTB4R · Sources: Hetionet, Reactome, WikiPathways

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LTB4R interacts with GNA15ProteinHetionet hetionet:interacts:1241-2769Inferred only
LTB4R interacts with GRK6ProteinHetionet hetionet:interacts:1241-2870Inferred only
LTB4R interacts with YWHAGProteinHetionet hetionet:interacts:1241-7532Inferred only
LTB4R participates in Class A/1 (Rhodopsin-like receptors)PathwayReactome R-HSA-373076Inferred only
LTB4R participates in Eicosanoid ligand-binding receptorsPathwayReactome R-HSA-391903Inferred only
LTB4R participates in Eicosanoid metabolism via lipooxygenases LOX PathwayWikiPathways WP4721Inferred only
LTB4R participates in G alpha (q) signalling eventsPathwayReactome R-HSA-416476Inferred only
LTB4R participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
LTB4R participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
LTB4R participates in GPCRs class A rhodopsin likePathwayWikiPathways WP455Inferred only
LTB4R participates in Leukotriene receptorsPathwayReactome R-HSA-391906Inferred only
LTB4R participates in Nucleotide GPCRsPathwayWikiPathways WP80Inferred only

Show the remaining 4

LTB4R participates in Resolvin E1 and resolvin D1 signaling decrease inflammationPathwayWikiPathways WP5191Inferred only
LTB4R participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
LTB4R participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
LTB4R participates in Spinal cord injuryPathwayWikiPathways WP2431Inferred only

Other names

12 names

Resolves to: LTB4R

Also called: BLTBLT1BLTRChemoattractant receptor-like 1CMKRL1G protein-coupled receptor 16GPR16LTB4-R 1LTB4-R1P2RY7P2Y purinoceptor 7P2Y7

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