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Proteins/UNIPROT:Q9H756
Pathogen-recognition receptor which mediates the activation of TRAF2- and TRAF6 NF-kappa-B signaling pathways and induces the expression of pro-inflammatory cytokines. In kidney, prevents infection by uropathogenic bacteria by inducing the production of cytokines, chemokines and antimicrobial substances. In gut, involved in host-microbiota interactions, plays a critical role in promoting the recruitment of immune cells and intestinal inflammation (By similarity)..
Function from UniProtKB (Q9H756), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
8 statements
8 statements · 2 reference databases · Subject: LRRC19 · Sources: gene ontology, Hetionet
1 name
Resolves to: LRRC19