Proteins/UNIPROT:P78385

KRT83

ProteinUNIPROT:P78385

Structural component of intermediate filaments in the hair cortex. Forms obligate heterodimers with type I hair keratins, which assemble into keratin intermediate filaments that contribute to the structural integrity and mechanical strength of the hair shaft..

Function from UniProtKB (P78385), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

3 rows

erythrokeratodermia variabilis has a germline basis in KRT83DiseaseGenCC HGNC:6460|MONDO:0017851Inferred only
monilethrix has a germline basis in KRT83DiseaseGenCC HGNC:6460|MONDO:0008009Inferred only
monilethrix-3 has a germline basis in KRT83DiseaseGenCC HGNC:6460|MONDO:0700342Inferred only

Statements

8 statements

8 statements · 2 reference databases · Subject: KRT83 · Sources: Hetionet, Reactome

Order

CRYGD covaries with KRT83ProteinHetionet hetionet:covaries:1421-3889Inferred only
KRT33B covaries with KRT83ProteinHetionet hetionet:covaries:3884-3889Inferred only
KRT83 covaries with KRT81ProteinHetionet hetionet:covaries:3887-3889Inferred only
KRT83 covaries with KRT86ProteinHetionet hetionet:covaries:3889-3892Inferred only
KRT83 interacts with UBCProteinHetionet hetionet:interacts:3889-7316Inferred only
KRT83 participates in Developmental BiologyPathwayReactome R-HSA-1266738Inferred only
KRT83 participates in Formation of the cornified envelopePathwayReactome R-HSA-6809371Inferred only
KRT83 participates in KeratinizationPathwayReactome R-HSA-6805567Inferred only

Other names

7 names

Resolves to: KRT83

Also called: Hair keratin K2.10hHb3K83Keratin-83KRTHB3Type II hair keratin Hb3Type-II keratin Kb23

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