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Proteins/UNIPROT:D3W0D1

KLRF2

Protein·UNIPROT:D3W0D1

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C-type lectin-like receptor involved in natural killer cell mediated cytotoxicity and cytokine secretion in keratinocytes via its interaction with CLEC2A. Triggers degranulation in a SYK-dependent manner and stimulates SYK phosphotyrosinylation without recruiting SYK directly..

Function from UniProtKB (D3W0D1), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

2 statements

2 statements · 2 reference databases · Subject: KLRF2 · Sources: gene ontology, Hetionet

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CLEC2A interacts with KLRF2ProteinHetionet hetionet:interacts:100431172-387836Inferred only
KLRF2 regulates positive regulation of cytokine productionBiological processgene ontology D3W0D1|GO:0001819Inferred only

Other names

2 names

Resolves to: KLRF2

Also called: Activating coreceptor NKp65Lectin-like receptor F2

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