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Proteins/UNIPROT:Q6UVW9

CLEC2A

Protein·UNIPROT:Q6UVW9

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Membrane-bound protein expressed mainly on keratinocytes which acts as a ligand to stimulate the activating receptor NKp65/KLRF2, expressed on the surface of natural killer (NK) cells. Facilitates thereby dedicated immune recognition of keratinocytes leading to natural killer cell mediated cytotoxicity. Also plays a role in modulating the extent of T-cell expansion..

Function from UniProtKB (Q6UVW9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

1 statement

1 statement · 1 reference database · Subject: CLEC2A · Sources: Hetionet

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CLEC2A interacts with KLRF2ProteinHetionet hetionet:interacts:100431172-387836Inferred only

Other names

4 names

Resolves to: CLEC2A

Also called: KACLKeratinocyte-associated C-type lectinPILARProliferation-induced lymphocyte-associated receptor

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