Proteins/UNIPROT:Q8IXV7

KLHDC8B

ProteinUNIPROT:Q8IXV7

Involved in pinching off the separated nuclei at the cleavage furrow and in cytokinesis. Required for mitotic integrity and maintenance of chromosomal stability. Protects cells against mitotic errors, centrosomal amplification, micronucleus formation and aneuploidy. Plays a key role of midbody function involving abscission of the daughter cells during cytokinesis and appropriate chromosomal and nuclear segregation into the daughter cells..

Function from UniProtKB (Q8IXV7), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

18 statements

18 statements · 1 reference database · Subject: KLHDC8B · Sources: Hetionet

Order

CDX1 covaries with KLHDC8BProteinHetionet hetionet:covaries:1044-200942Inferred only
DIO3 covaries with KLHDC8BProteinHetionet hetionet:covaries:1735-200942Inferred only
H2BC4; H2BC6; H2BC7; H2BC8; H2BC10 covaries with KLHDC8BProteinHetionet hetionet:covaries:200942-8339Inferred only
KLHDC8B covaries with HCAR2ProteinHetionet hetionet:covaries:200942-338442Inferred only
KLHDC8B covaries with JUNBProteinHetionet hetionet:covaries:200942-3726Inferred only
KLHDC8B covaries with MIDNProteinHetionet hetionet:covaries:200942-90007Inferred only
KLHDC8B covaries with NDNProteinHetionet hetionet:covaries:200942-4692Inferred only
OR2AT4 covaries with KLHDC8BProteinHetionet hetionet:covaries:200942-341152Inferred only
KLHDC8B covaries with SPRED3ProteinHetionet hetionet:covaries:200942-399473Inferred only
KLHDC8B covaries with SSRP1ProteinHetionet hetionet:covaries:200942-6749Inferred only
KLHDC8B covaries with XAB2ProteinHetionet hetionet:covaries:200942-56949Inferred only
KLHDC8B covaries with ZNF26ProteinHetionet hetionet:covaries:200942-7574Inferred only

Show the remaining 6

ZNF300 covaries with KLHDC8BProteinHetionet hetionet:covaries:200942-91975Inferred only
ZNF354B covaries with KLHDC8BProteinHetionet hetionet:covaries:117608-200942Inferred only
ZNF354C covaries with KLHDC8BProteinHetionet hetionet:covaries:200942-30832Inferred only
ZNF771 covaries with KLHDC8BProteinHetionet hetionet:covaries:200942-51333Inferred only
ZYX covaries with KLHDC8BProteinHetionet hetionet:covaries:200942-7791Inferred only
UBC interacts with KLHDC8BProteinHetionet hetionet:interacts:200942-7316Inferred only

Other names

1 name

Resolves to: KLHDC8B

Also called: Kelch domain-containing protein 8B

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