Proteins/UNIPROT:Q2M2Z5

KIZ

ProteinUNIPROT:Q2M2Z5

Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole..

Function from UniProtKB (Q2M2Z5), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

3 rows

KIZ-related retinopathy has a germline basis in KIZDiseaseGenCC HGNC:15865|MONDO:0700232Inferred only
retinitis pigmentosa has a germline basis in KIZDiseaseGenCC HGNC:15865|MONDO:0019200Inferred only
retinitis pigmentosa 69 has a germline basis in KIZDiseaseGenCC HGNC:15865|MONDO:0014345Inferred only

Statements

14 statements

14 statements · 2 reference databases · Subject: KIZ · Sources: Hetionet, WikiPathways

Order

KIZ covaries with CARS2ProteinHetionet hetionet:covaries:55857-79587Inferred only
KIZ covaries with SPOCD1ProteinHetionet hetionet:covaries:55857-90853Inferred only
TEX28; TEX28P1; TEX28P2 covaries with KIZProteinHetionet hetionet:covaries:1527-55857Inferred only
CEP72 interacts with KIZProteinHetionet hetionet:interacts:55722-55857Inferred only
UBD interacts with KIZProteinHetionet hetionet:interacts:10537-55857Inferred only
KIZ participates in CiliopathiesPathwayWikiPathways WP4803Inferred only
AKT1 increases the expression of KIZProteinHetionet hetionet:regulates:207-55857Inferred only
AKT2 increases the expression of KIZProteinHetionet hetionet:regulates:208-55857Inferred only
CRKL increases the expression of KIZProteinHetionet hetionet:regulates:1399-55857Inferred only
DVL2 increases the expression of KIZProteinHetionet hetionet:regulates:1856-55857Inferred only
MEGF9 increases the expression of KIZProteinHetionet hetionet:regulates:1955-55857Inferred only
NRBP2 increases the expression of KIZProteinHetionet hetionet:regulates:340371-55857Inferred only

Show the remaining 2

RPS6 increases the expression of KIZProteinHetionet hetionet:regulates:6194-55857Inferred only
SMAD4 increases the expression of KIZProteinHetionet hetionet:regulates:4089-55857Inferred only

Other names

5 names

Resolves to: KIZ

Also called: C20orf19Centrosomal protein kizunaNCRNA00153PLK1S1Polo-like kinase 1 substrate 1

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