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Proteins/UNIPROT:Q2VIQ3

KIF4B

Protein·UNIPROT:Q2VIQ3

Open in the graph

Iron-sulfur (Fe-S) cluster binding motor protein that has a role in chromosome segregation during mitosis (By similarity). Translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis (By similarity). May play a role in mitotic chromosomal positioning and bipolar spindle stabilization (By similarity)..

Function from UniProtKB (Q2VIQ3), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

23 statements

23 statements · 3 reference databases · Subject: KIF4B · Sources: Hetionet, Reactome, UniProt

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SUMO2 interacts with KIF4BProteinHetionet hetionet:interacts:285643-6613Inferred only
UBC interacts with KIF4BProteinHetionet hetionet:interacts:285643-7316Inferred only
KIF4B participates in Adaptive Immune SystemPathwayReactome R-HSA-1280218Inferred only
KIF4B participates in Affinity selection of immunoglobulinsPathwayReactome R-HSA-9938027Inferred only
KIF4B participates in Axon guidancePathwayReactome R-HSA-422475Inferred only
KIF4B participates in COPI-dependent Golgi-to-ER retrograde trafficPathwayReactome R-HSA-6811434Inferred only
KIF4B participates in Developmental BiologyPathwayReactome R-HSA-1266738Inferred only
KIF4B participates in Factors involved in megakaryocyte development and platelet productionPathwayReactome R-HSA-983231Inferred only
KIF4B participates in Golgi-to-ER retrograde transportPathwayReactome R-HSA-8856688Inferred only
KIF4B participates in HemostasisPathwayReactome R-HSA-109582Inferred only
KIF4B participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
KIF4B participates in Immunoglobulin maturationPathwayReactome R-HSA-9938026Inferred only

Show the remaining 11

KIF4B participates in Intra-Golgi and retrograde Golgi-to-ER trafficPathwayReactome R-HSA-6811442Inferred only
KIF4B participates in KinesinsPathwayReactome R-HSA-983189Inferred only
KIF4B participates in L1CAM interactionsPathwayReactome R-HSA-373760Inferred only
KIF4B participates in Membrane TraffickingPathwayReactome R-HSA-199991Inferred only
KIF4B participates in MHC class II antigen presentationPathwayReactome R-HSA-2132295Inferred only
KIF4B participates in Nervous system developmentPathwayReactome R-HSA-9675108Inferred only
KIF4B participates in Processing of antigen in germinal center B cellsPathwayReactome R-HSA-9979719Inferred only
KIF4B participates in Recycling pathway of L1PathwayReactome R-HSA-437239Inferred only
KIF4B participates in Vesicle-mediated transportPathwayReactome R-HSA-5653656Inferred only
KIF4B requires the cofactor di-mu-sulfido-diironCompoundUniProt Q2VIQ3Inferred only
KIF4B requires the cofactor tetra-mu3-sulfido-tetraironCompoundUniProt Q2VIQ3Inferred only

Other names

2 names

Resolves to: KIF4B

Also called: Chromokinesin-BChromosome-associated kinesin KIF4B

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