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Proteins/UNIPROT:Q96L42

KCNH8

Protein·UNIPROT:Q96L42Voltage-gated delayed rectifier potassium channel KCNH8

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Pore-forming (alpha) subunit of a voltage-gated delayed rectifier potassium channel that mediates outward-rectifying potassium currents. Elicits a slowly activating, non-inactivating and slowly deactivation outwards potassium current at depolarizating voltages from -30 mV to +50mV. Shows no obvious change in the activation rate from different holding potentials. Activation is strongly dependent on the pH of the external solution (By similarity)..

Function from UniProtKB (Q96L42), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

5 statements

5 statements · 3 reference databases · Subject: KCNH8 · Sources: gene ontology, Reactome, Rhea

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KCNH8 participates in Neuronal SystemPathwayReactome R-HSA-112316Inferred only
KCNH8 participates in Potassium ChannelsPathwayReactome R-HSA-1296071Inferred only
KCNH8 participates in Voltage gated Potassium channelsPathwayReactome R-HSA-1296072Inferred only
KCNH8 regulates regulation of membrane potentialBiological processgene ontology Q96L42|GO:0042391Inferred only
K(+) is transported by KCNH8CompoundRhea RHEA:29463Inferred only

Reactions

1 reaction

K(+)K(+)
Transported by ANO9 or HTR3E or KCNU1 or KCNJ18 or TMEM150C or KCNK1 or KCNK3 or GRIN2D or KCNN4 or KCNQ3 or KCNQ2 or HCN1 and 136 more alternatives
Reaction pageDirection not assertedBalanced
Rhea RHEA:29463CC BY 4.0Reference data

Other names

7 names

Resolves to: KCNH8

Also called: ELK channel 3ELK1ELK3Ether-a-go-go-like potassium channel 3hElk-1Potassium voltage-gated channel subfamily H member 8Voltage-gated potassium channel subunit Kv12.1

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