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Proteins/UNIPROT:Q9UPP2

IQSEC3

Protein·UNIPROT:Q9UPP2

Open in the graph

Acts as a guanine nucleotide exchange factor (GEF) for ARF1..

Function from UniProtKB (Q9UPP2), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

1 row

intellectual disability has a germline basis in IQSEC3DiseaseGenCC HGNC:29193|MONDO:0001071Inferred only

Statements

8 statements

8 statements · 3 reference databases · Subject: IQSEC3 · Sources: gene ontology, Hetionet, Reactome

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TEX101 covaries with IQSEC3ProteinHetionet hetionet:covaries:440073-83639Inferred only
IQSEC3 participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
IQSEC3 participates in Generic Transcription PathwayPathwayReactome R-HSA-212436Inferred only
IQSEC3 participates in NPAS4 regulates expression of target genesPathwayReactome R-HSA-9768919Inferred only
IQSEC3 participates in RNA Polymerase II TranscriptionPathwayReactome R-HSA-73857Inferred only
IQSEC3 participates in Transcriptional Regulation by NPAS4PathwayReactome R-HSA-9634815Inferred only
IQSEC3 regulates regulation of ARF protein signal transductionBiological processgene ontology Q9UPP2|GO:0032012Inferred only
IQSEC3 regulates regulation of postsynaptic neurotransmitter receptor internalizationBiological processgene ontology Q9UPP2|GO:0099149Inferred only

Other names

2 names

Resolves to: IQSEC3

Also called: IQ motif and SEC7 domain-containing protein 3KIAA1110

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