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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:Q8NFR9

IL17RE

Protein·UNIPROT:Q8NFR9

Open in the graph

Specific functional receptor for IL17C. May be signaling through the NF-kappa-B and MAPK pathways. May require TRAF3IP2 /ACT1 for signaling. May be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors..

Function from UniProtKB (Q8NFR9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

10 statements

10 statements · 4 reference databases · Subject: IL17RE · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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IL17RE covaries with DRG2ProteinHetionet hetionet:covaries:132014-1819Inferred only
NUP188 covaries with IL17REProteinHetionet hetionet:covaries:132014-23511Inferred only
PLPP5 covaries with IL17REProteinHetionet hetionet:covaries:132014-84513Inferred only
IL17RA interacts with IL17REProteinHetionet hetionet:interacts:132014-23765Inferred only
IL17RE participates in Cytokine Signaling in Immune systemPathwayReactome R-HSA-1280215Inferred only
IL17RE participates in IL17 signalingPathwayWikiPathways WP2112Inferred only
IL17RE participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
IL17RE participates in Interleukin-17 signalingPathwayReactome R-HSA-448424Inferred only
IL17RE participates in Signaling by InterleukinsPathwayReactome R-HSA-449147Inferred only
IL17RE regulates positive regulation of cytokine production involved in inflammatory responseBiological processgene ontology Q8NFR9|GO:1900017Inferred only

Other names

2 names

Resolves to: IL17RE

Also called: IL-17 receptor EIL-17RE

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