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Proteins/UNIPROT:P32881

IFNA8

Protein·UNIPROT:P32881

Open in the graph

Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.

Function from UniProtKB (P32881), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

38 statements

38 statements · 3 reference databases · Subject: IFNA8 · Sources: Hetionet, Reactome, WikiPathways

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GPR34 covaries with IFNA8ProteinHetionet hetionet:covaries:2857-3445Inferred only
IFNA8 covaries with IFNA21ProteinHetionet hetionet:covaries:3445-3452Inferred only
IFNA8 covaries with KIAA1614ProteinHetionet hetionet:covaries:3445-57710Inferred only
IFNA8 covaries with OR56B1ProteinHetionet hetionet:covaries:3445-387748Inferred only
IFNA8 covaries with REEP2ProteinHetionet hetionet:covaries:3445-51308Inferred only
APP interacts with IFNA8ProteinHetionet hetionet:interacts:3445-351Inferred only
IFNA8 interacts with IFNAR1ProteinHetionet hetionet:interacts:3445-3454Inferred only
IFNA8 interacts with IFNAR2ProteinHetionet hetionet:interacts:3445-3455Inferred only
IFNA8 participates in Cancer pathwaysPathwayWikiPathways WP5434Inferred only
IFNA8 participates in Cytokine Signaling in Immune systemPathwayReactome R-HSA-1280215Inferred only
IFNA8 participates in Cytosolic DNA sensing pathwayPathwayWikiPathways WP4655Inferred only
IFNA8 participates in DDX58/IFIH1-mediated induction of interferon-alpha/betaPathwayReactome R-HSA-168928Inferred only

Show the remaining 26

IFNA8 participates in DiseasePathwayReactome R-HSA-1643685Inferred only
IFNA8 participates in Evasion by RSV of host interferon responsesPathwayReactome R-HSA-9833109Inferred only
IFNA8 participates in Factors involved in megakaryocyte development and platelet productionPathwayReactome R-HSA-983231Inferred only
IFNA8 participates in HemostasisPathwayReactome R-HSA-109582Inferred only
IFNA8 participates in Hepatitis B infectionPathwayWikiPathways WP4666Inferred only
IFNA8 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
IFNA8 participates in Infectious diseasePathwayReactome R-HSA-5663205Inferred only
IFNA8 participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only
IFNA8 participates in Interferon alpha/beta signalingPathwayReactome R-HSA-909733Inferred only
IFNA8 participates in Interferon mediated signalingPathwayWikiPathways WP4558Inferred only
IFNA8 participates in Interferon SignalingPathwayReactome R-HSA-913531Inferred only
IFNA8 participates in Measles virus infectionPathwayWikiPathways WP4630Inferred only
IFNA8 participates in Overview of proinflammatory and profibrotic mediatorsPathwayWikiPathways WP5095Inferred only
IFNA8 participates in PI3K Akt signalingPathwayWikiPathways WP4172Inferred only
IFNA8 participates in Regulation of IFNA/IFNB signalingPathwayReactome R-HSA-912694Inferred only
IFNA8 participates in Regulation of toll like receptor signalingPathwayWikiPathways WP1449Inferred only
IFNA8 participates in Respiratory Syncytial Virus Infection PathwayPathwayReactome R-HSA-9820952Inferred only
IFNA8 participates in RSV-host interactionsPathwayReactome R-HSA-9833110Inferred only
IFNA8 participates in SARS coronavirus and innate immunityPathwayWikiPathways WP4912Inferred only
IFNA8 participates in SARS-CoV InfectionsPathwayReactome R-HSA-9679506Inferred only
IFNA8 participates in SARS-CoV-2 activates/modulates innate and adaptive immune responsesPathwayReactome R-HSA-9705671Inferred only
IFNA8 participates in SARS-CoV-2 InfectionPathwayReactome R-HSA-9694516Inferred only
IFNA8 participates in SARS-CoV-2-host interactionsPathwayReactome R-HSA-9705683Inferred only
IFNA8 participates in Toll like receptor signalingPathwayWikiPathways WP75Inferred only
IFNA8 participates in TRAF6 mediated IRF7 activationPathwayReactome R-HSA-933541Inferred only
IFNA8 participates in Viral Infection PathwaysPathwayReactome R-HSA-9824446Inferred only

Other names

4 names

Resolves to: IFNA8

Also called: IFN-alpha-8Interferon alpha-BInterferon alpha-B2LeIF B

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