Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Proteins/UNIPROT:P01569

IFNA5

Protein·UNIPROT:P01569

Open in the graph

Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.

Function from UniProtKB (P01569), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

32 statements

32 statements · 3 reference databases · Subject: IFNA5 · Sources: Hetionet, Reactome, WikiPathways

Search this listOrder

APP interacts with IFNA5ProteinHetionet hetionet:interacts:3442-351Inferred only
IFNA5 interacts with IFNAR2ProteinHetionet hetionet:interacts:3442-3455Inferred only
IFNA5 participates in Cancer pathwaysPathwayWikiPathways WP5434Inferred only
IFNA5 participates in Cytokine Signaling in Immune systemPathwayReactome R-HSA-1280215Inferred only
IFNA5 participates in Cytosolic DNA sensing pathwayPathwayWikiPathways WP4655Inferred only
IFNA5 participates in DDX58/IFIH1-mediated induction of interferon-alpha/betaPathwayReactome R-HSA-168928Inferred only
IFNA5 participates in DiseasePathwayReactome R-HSA-1643685Inferred only
IFNA5 participates in Evasion by RSV of host interferon responsesPathwayReactome R-HSA-9833109Inferred only
IFNA5 participates in Factors involved in megakaryocyte development and platelet productionPathwayReactome R-HSA-983231Inferred only
IFNA5 participates in HemostasisPathwayReactome R-HSA-109582Inferred only
IFNA5 participates in Hepatitis B infectionPathwayWikiPathways WP4666Inferred only
IFNA5 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only

Show the remaining 20

IFNA5 participates in Infectious diseasePathwayReactome R-HSA-5663205Inferred only
IFNA5 participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only
IFNA5 participates in Interferon alpha/beta signalingPathwayReactome R-HSA-909733Inferred only
IFNA5 participates in Interferon mediated signalingPathwayWikiPathways WP4558Inferred only
IFNA5 participates in Interferon SignalingPathwayReactome R-HSA-913531Inferred only
IFNA5 participates in Measles virus infectionPathwayWikiPathways WP4630Inferred only
IFNA5 participates in Overview of proinflammatory and profibrotic mediatorsPathwayWikiPathways WP5095Inferred only
IFNA5 participates in PI3K Akt signalingPathwayWikiPathways WP4172Inferred only
IFNA5 participates in Regulation of IFNA/IFNB signalingPathwayReactome R-HSA-912694Inferred only
IFNA5 participates in Regulation of toll like receptor signalingPathwayWikiPathways WP1449Inferred only
IFNA5 participates in Respiratory Syncytial Virus Infection PathwayPathwayReactome R-HSA-9820952Inferred only
IFNA5 participates in RSV-host interactionsPathwayReactome R-HSA-9833110Inferred only
IFNA5 participates in SARS coronavirus and innate immunityPathwayWikiPathways WP4912Inferred only
IFNA5 participates in SARS-CoV InfectionsPathwayReactome R-HSA-9679506Inferred only
IFNA5 participates in SARS-CoV-2 activates/modulates innate and adaptive immune responsesPathwayReactome R-HSA-9705671Inferred only
IFNA5 participates in SARS-CoV-2 InfectionPathwayReactome R-HSA-9694516Inferred only
IFNA5 participates in SARS-CoV-2-host interactionsPathwayReactome R-HSA-9705683Inferred only
IFNA5 participates in Toll like receptor signalingPathwayWikiPathways WP75Inferred only
IFNA5 participates in TRAF6 mediated IRF7 activationPathwayReactome R-HSA-933541Inferred only
IFNA5 participates in Viral Infection PathwaysPathwayReactome R-HSA-9824446Inferred only

Other names

4 names

Resolves to: IFNA5

Also called: IFN-alpha-5Interferon alpha-61Interferon alpha-GLeIF G

← Every protein Find it in the graph →