IFIT1B

IFIT1B is likely non-functional, lacking the critical antiviral role of IFIT1. Unlike IFIT1, which is essential in the innate immune response as part of an interferon-dependent multiprotein complex, IFIT1B does not prevent the translation of viral RNAs that lack host-specific 2'-O-methylation at their 5' cap. Consequently, it probably cannot inhibit their translation by competing with the host translation machinery..

Function from UniProtKB (Q5T764), read 2026-09-23. CC BY 4.0.