Proteins/UNIPROT:Q659A1

ICE2

ProteinUNIPROT:Q659A1

Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III..

Function from UniProtKB (Q659A1), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

13 statements

13 statements · 3 reference databases · Subject: ICE2 · Sources: gene ontology, Hetionet, Reactome

Order

ROS1 covaries with ICE2ProteinHetionet hetionet:covaries:6098-79664Inferred only
SENP5 covaries with ICE2ProteinHetionet hetionet:covaries:205564-79664Inferred only
UBC interacts with ICE2ProteinHetionet hetionet:interacts:7316-79664Inferred only
ICE2 participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
ICE2 participates in RNA polymerase II transcribes snRNA genesPathwayReactome R-HSA-6807505Inferred only
ICE2 participates in RNA Polymerase II TranscriptionPathwayReactome R-HSA-73857Inferred only
ICE2 regulates positive regulation of snRNA transcription by RNA polymerase IIBiological processgene ontology Q659A1|GO:1905382Inferred only
ICE2 regulates positive regulation of transcription by RNA polymerase IIIBiological processgene ontology Q659A1|GO:0045945Inferred only
ACO2 increases the expression of ICE2ProteinHetionet hetionet:regulates:50-79664Inferred only
GLDC decreases the expression of ICE2ProteinHetionet hetionet:regulates:2731-79664Inferred only
HLA-DRB5 increases the expression of ICE2ProteinHetionet hetionet:regulates:3127-79664Inferred only
PRKACA increases the expression of ICE2ProteinHetionet hetionet:regulates:5566-79664Inferred only

Show the remaining 1

TNIP1 increases the expression of ICE2ProteinHetionet hetionet:regulates:10318-79664Inferred only

Other names

4 names

Resolves to: ICE2

Also called: BRCC1Interactor of little elongator complex ELL subunit 2NARG2NMDA receptor-regulated protein 2

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