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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:Q9NQE9

HINT3

Protein·UNIPROT:Q9NQE9Adenosine 5'-monophosphoramidase HINT3

Open in the graph

Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2. Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase. Hydrolyzes 3-indolepropionic acyl-adenylate and fluorogenic purine nucleoside tryptamine phosphoramidates in vitro..

Function from UniProtKB (Q9NQE9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

9 statements

9 statements · 3 reference databases · Subject: HINT3 · Sources: Bgee, Hetionet, Rhea

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HINT3 is expressed in biceps brachiiAnatomyBgee ENSG00000111911Inferred only
HINT3 is expressed in C1 segment of cervical spinal cordAnatomyBgee ENSG00000111911Inferred only
HINT3 is expressed in endothelial cellCell typeBgee ENSG00000111911Inferred only
HINT3 is expressed in gastrocnemiusAnatomyBgee ENSG00000111911Inferred only
HINT3 is expressed in ponsAnatomyBgee ENSG00000111911Inferred only
HINT3 is expressed in vastus lateralisAnatomyBgee ENSG00000111911Inferred only
APP interacts with HINT3ProteinHetionet hetionet:interacts:135114-351Inferred only
UBC interacts with HINT3ProteinHetionet hetionet:interacts:135114-7316Inferred only
adenosine 5'-phosphoramidate is a substrate of HINT3CompoundRhea RHEA:67916Inferred only

Reactions

1 reaction

adenosine 5'-phosphoramidate+waterammonium+AMP
Catalysed by HINT1 or FHIT or HINT2 or HINT3
Reaction pageDirection not assertedBalanced
Rhea RHEA:67916CC BY 4.0Reference data

Other names

2 names

Resolves to: HINT3

Also called: HINT-3Histidine triad nucleotide-binding protein 3

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