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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:Q8N4P3

HDDC3

Protein·UNIPROT:Q8N4P3

Open in the graph

ppGpp hydrolyzing enzyme involved in starvation response..

Function from UniProtKB (Q8N4P3), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

5 statements

5 statements · 2 reference databases · Subject: HDDC3 · Sources: Hetionet, UniProt

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PLIN5 covaries with HDDC3ProteinHetionet hetionet:covaries:374659-440503Inferred only
APP interacts with HDDC3ProteinHetionet hetionet:interacts:351-374659Inferred only
NMI interacts with HDDC3ProteinHetionet hetionet:interacts:374659-9111Inferred only
UBC interacts with HDDC3ProteinHetionet hetionet:interacts:374659-7316Inferred only
HDDC3 requires the cofactor Mn(2+)CompoundUniProt Q8N4P3Inferred only

Reactions

1 reaction

CHEBI:77828+waterGDP+diphosphate(3-)+hydron
Catalysed by HDDC3
Reaction pageDirection not assertedBalanced
Rhea RHEA:14253CC BY 4.0Reference data

Other names

6 names

Resolves to: HDDC3

Also called: (ppGpp)asediphosphateHD domain-containing protein 3MESH1Metazoan SpoT homolog 1Penta-phosphate guanosine-3'-pyrophosphohydrolase

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