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Proteins/UNIPROT:Q6NXT2
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Hominid-specific H3.5/H3F3C preferentially colocalizes with euchromatin, and it is associated with actively transcribed genes..
Function from UniProtKB (Q6NXT2), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
4 statements
4 statements · 2 reference databases · Subject: H3-5 · Sources: gene ontology, Hetionet
3 names
Resolves to: H3-5