Proteins/UNIPROT:P02724

GYPA

ProteinUNIPROT:P02724

Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane. Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane..

(Microbial infection) Appears to be a receptor for Hepatitis A virus (HAV)..

(Microbial infection) Receptor for P.falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans..

Function from UniProtKB (P02724), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

5 statements

5 statements · 3 reference databases · Subject: GYPA · Sources: Hetionet, Reactome, WikiPathways

Order

GYPA covaries with TMEM254ProteinHetionet hetionet:covaries:2993-80195Inferred only
GYPA participates in Cell surface interactions at the vascular wallPathwayReactome R-HSA-202733Inferred only
GYPA participates in ErythropoiesisPathwayWikiPathways WP5607Inferred only
GYPA participates in Hematopoietic stem cell differentiationPathwayWikiPathways WP2849Inferred only
GYPA participates in HemostasisPathwayReactome R-HSA-109582Inferred only

Other names

6 names

Resolves to: GYPA

Also called: CD antigen CD235aGPAMN sialoglycoproteinMNSPAS-2Sialoglycoprotein alpha

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