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Proteins/UNIPROT:Q4G148

GXYLT1

Protein·UNIPROT:Q4G148

Open in the graph

Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose..

Function from UniProtKB (Q4G148), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

4 statements

4 statements · 2 reference databases · Subject: GXYLT1 · Sources: Hetionet, Rhea

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TNFSF9 covaries with GXYLT1ProteinHetionet hetionet:covaries:283464-8744Inferred only
TRAF6 interacts with GXYLT1ProteinHetionet hetionet:interacts:283464-7189Inferred only
UBC interacts with GXYLT1ProteinHetionet hetionet:interacts:283464-7316Inferred only
UDP-alpha-D-xylose is a substrate of GXYLT1CompoundRhea RHEA:56064Inferred only

Reactions

1 reaction

3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein]+UDP-alpha-D-xylose3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein]+UDP+hydron
Catalysed by GXYLT2 or GXYLT1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:56064CC BY 4.0Reference data

Other names

2 names

Resolves to: GXYLT1

Also called: GLT8D3Glycosyltransferase 8 domain-containing protein 3

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