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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:O14653

GOSR2

Protein·UNIPROT:O14653

Open in the graph

Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network..

Function from UniProtKB (O14653), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

3 rows

muscular dystrophy, congenital, with or without seizures has a germline basis in GOSR2DiseaseGenCC HGNC:4431|MONDO:0859336Inferred only
progressive myoclonic epilepsy type 6 has a germline basis in GOSR2DiseaseGenCC HGNC:4431|MONDO:0013526Inferred only
progressive myoclonus epilepsy has a germline basis in GOSR2DiseaseGenCC HGNC:4431|MONDO:0020074Inferred only

Statements

25 statements

25 statements · 2 reference databases · Subject: GOSR2 · Sources: Hetionet, Reactome

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APP interacts with GOSR2ProteinHetionet hetionet:interacts:351-9570Inferred only
STX5 interacts with GOSR2ProteinHetionet hetionet:interacts:6811-9570Inferred only
UBC interacts with GOSR2ProteinHetionet hetionet:interacts:7316-9570Inferred only
USO1 interacts with GOSR2ProteinHetionet hetionet:interacts:8615-9570Inferred only
GOSR2 participates in Asparagine N-linked glycosylationPathwayReactome R-HSA-446203Inferred only
GOSR2 participates in Cargo concentration in the ERPathwayReactome R-HSA-5694530Inferred only
GOSR2 participates in Cellular responses to stimuliPathwayReactome R-HSA-8953897Inferred only
GOSR2 participates in Cellular responses to stressPathwayReactome R-HSA-2262752Inferred only
GOSR2 participates in COPI-mediated anterograde transportPathwayReactome R-HSA-6807878Inferred only
GOSR2 participates in COPII-mediated vesicle transportPathwayReactome R-HSA-204005Inferred only
GOSR2 participates in ER to Golgi Anterograde TransportPathwayReactome R-HSA-199977Inferred only
GOSR2 participates in Intra-Golgi and retrograde Golgi-to-ER trafficPathwayReactome R-HSA-6811442Inferred only

Show the remaining 13

GOSR2 participates in Intra-Golgi trafficPathwayReactome R-HSA-6811438Inferred only
GOSR2 participates in IRE1alpha activates chaperonesPathwayReactome R-HSA-381070Inferred only
GOSR2 participates in Membrane TraffickingPathwayReactome R-HSA-199991Inferred only
GOSR2 participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
GOSR2 participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
GOSR2 participates in Transport to the Golgi and subsequent modificationPathwayReactome R-HSA-948021Inferred only
GOSR2 participates in Unfolded Protein Response (UPR)PathwayReactome R-HSA-381119Inferred only
GOSR2 participates in Vesicle-mediated transportPathwayReactome R-HSA-5653656Inferred only
GOSR2 participates in XBP1(S) activates chaperone genesPathwayReactome R-HSA-381038Inferred only
GLRX2 increases the expression of GOSR2ProteinHetionet hetionet:regulates:51022-9570Inferred only
KDM2B increases the expression of GOSR2ProteinHetionet hetionet:regulates:84678-9570Inferred only
TRAPPC3 increases the expression of GOSR2ProteinHetionet hetionet:regulates:27095-9570Inferred only
TRIM13 increases the expression of GOSR2ProteinHetionet hetionet:regulates:10206-9570Inferred only

Other names

3 names

Resolves to: GOSR2

Also called: 27 kDa Golgi SNARE proteinGS27Membrin

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