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Proteins/UNIPROT:P01148

GNRH1

Protein·UNIPROT:P01148

Open in the graph

Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.

Function from UniProtKB (P01148), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

2 rows

hypogonadotropic hypogonadism has a germline basis in GNRH1DiseaseGenCC HGNC:4419|MONDO:0018555Inferred only
hypogonadotropic hypogonadism 12 with or without anosmia has a germline basis in GNRH1DiseaseGenCC HGNC:4419|MONDO:0013914Inferred only

Statements

17 statements

17 statements · 4 reference databases · Subject: GNRH1 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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KNL1 covaries with GNRH1ProteinHetionet hetionet:covaries:2796-57082Inferred only
GNRH1 interacts with GNRHRProteinHetionet hetionet:interacts:2796-2798Inferred only
GNRH1 interacts with MEP1AProteinHetionet hetionet:interacts:2796-4224Inferred only
GNRH1 participates in Class A/1 (Rhodopsin-like receptors)PathwayReactome R-HSA-373076Inferred only
GNRH1 participates in G alpha (q) signalling eventsPathwayReactome R-HSA-416476Inferred only
GNRH1 participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
GNRH1 participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
GNRH1 participates in Hormonal control of pubertal growth spurtPathwayWikiPathways WP4194Inferred only
GNRH1 participates in Hormone ligand-binding receptorsPathwayReactome R-HSA-375281Inferred only
GNRH1 participates in Kallmann syndromePathwayWikiPathways WP5074Inferred only
GNRH1 participates in Orexin receptor pathwayPathwayWikiPathways WP5094Inferred only
GNRH1 participates in Prader Willi and Angelman syndromePathwayWikiPathways WP3998Inferred only

Show the remaining 5

GNRH1 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
GNRH1 participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
GNRH1 regulates negative regulation of apoptotic processBiological processgene ontology P01148|GO:0043066Inferred only
GNRH1 regulates negative regulation of immature T cell proliferationBiological processgene ontology P01148|GO:0033087Inferred only
GNRH1 regulates regulation of signalingBiological processgene ontology P01148|GO:0023051Inferred only

Other names

13 names

Resolves to: GNRH1

Also called: ; GnRH-associated peptide 1GNRHGnRH-associated peptide IGnRH-IGonadoliberin IGonadorelinGonadotropin-releasing hormone IGRHLH-RH ILHRHLuliberin ILuteinizing hormone-releasing hormone IProgonadoliberin I

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