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Proteins/UNIPROT:Q5TBA9

FRY

Protein·UNIPROT:Q5TBA9

Open in the graph

Plays a crucial role in the structural integrity of mitotic centrosomes and in the maintenance of spindle bipolarity by promoting PLK1 activity at the spindle poles in early mitosis. May function as a scaffold promoting the interaction between AURKA and PLK1, thereby enhancing AURKA-mediated PLK1 phosphorylation..

Function from UniProtKB (Q5TBA9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

1 row

neurodevelopmental disorder has a germline basis in FRYDiseaseGenCC HGNC:20367|MONDO:0700092Inferred only

Statements

4 statements

4 statements · 2 reference databases · Subject: FRY · Sources: gene ontology, Hetionet

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ALAS1 covaries with FRYProteinHetionet hetionet:covaries:10129-211Inferred only
NUDT10 covaries with FRYProteinHetionet hetionet:covaries:10129-170685Inferred only
UBC interacts with FRYProteinHetionet hetionet:interacts:10129-7316Inferred only
FRY regulates negative regulation of tubulin deacetylationBiological processgene ontology Q5TBA9|GO:1904428Inferred only

Other names

3 names

Resolves to: FRY

Also called: C13orf14furry homologProtein furry homolog

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