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Proteins/UNIPROT:Q12946

FOXF1

Protein·UNIPROT:Q12946

Open in the graph

Probable transcription activator for a number of lung-specific genes.

Function from UniProtKB (Q12946), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

1 row

alveolar capillary dysplasia with misalignment of pulmonary veins has a germline basis in FOXF1DiseaseGenCC HGNC:3809|MONDO:0009934Inferred only

Statements

16 statements

16 statements · 3 reference databases · Subject: FOXF1 · Sources: gene ontology, Hetionet, Reactome

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CDKN2AIP covaries with FOXF1ProteinHetionet hetionet:covaries:2294-55602Inferred only
CWH43 covaries with FOXF1ProteinHetionet hetionet:covaries:2294-80157Inferred only
FOXF1 participates in Adherens junctions interactionsPathwayReactome R-HSA-418990Inferred only
FOXF1 participates in Cell junction organizationPathwayReactome R-HSA-446728Inferred only
FOXF1 participates in Cell-Cell communicationPathwayReactome R-HSA-1500931Inferred only
FOXF1 participates in Cell-cell junction organizationPathwayReactome R-HSA-421270Inferred only
FOXF1 participates in Developmental BiologyPathwayReactome R-HSA-1266738Inferred only
FOXF1 participates in Formation of lateral plate mesodermPathwayReactome R-HSA-9758920Inferred only
FOXF1 participates in GastrulationPathwayReactome R-HSA-9758941Inferred only
FOXF1 participates in Regulation of CDH11 Expression and FunctionPathwayReactome R-HSA-9759475Inferred only
FOXF1 participates in Regulation of CDH11 gene transcriptionPathwayReactome R-HSA-9762293Inferred only
FOXF1 participates in Regulation of Expression and Function of Type II Classical CadherinsPathwayReactome R-HSA-9764260Inferred only

Show the remaining 4

FOXF1 participates in Regulation of Homotypic Cell-Cell AdhesionPathwayReactome R-HSA-9759476Inferred only
FOXF1 regulates positive regulation of DNA-templated transcriptionBiological processgene ontology Q12946|GO:0045893Inferred only
FOXF1 regulates positive regulation of transcription by RNA polymerase IIBiological processgene ontology Q12946|GO:0045944Inferred only
FOXF1 regulates regulation of transcription by RNA polymerase IIBiological processgene ontology Q12946|GO:0006357Inferred only

Other names

6 names

Resolves to: FOXF1

Also called: FKHL5Forkhead-related activator 1Forkhead-related protein FKHL5Forkhead-related transcription factor 1FREAC-1FREAC1

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