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Proteins/UNIPROT:Q4G163
Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Plays a vital role in modulating the ubiquitilation of CCNB1 and CDK1 during gametogenesis..
Function from UniProtKB (Q4G163), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
10 statements
10 statements · 2 reference databases · Subject: FBXO43 · Sources: gene ontology, Hetionet
3 names
Resolves to: FBXO43