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Proteins/UNIPROT:Q96ME1

FBXL18

Protein·UNIPROT:Q96ME1

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Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex..

Function from UniProtKB (Q96ME1), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

28 statements

28 statements · 3 reference databases · Subject: FBXL18 · Sources: gene ontology, Hetionet, Reactome

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FBXL18 covaries with AP5Z1ProteinHetionet hetionet:covaries:80028-9907Inferred only
ARHGAP40 covaries with FBXL18ProteinHetionet hetionet:covaries:343578-80028Inferred only
SNAPC4 covaries with FBXL18ProteinHetionet hetionet:covaries:6621-80028Inferred only
TECPR1 covaries with FBXL18ProteinHetionet hetionet:covaries:25851-80028Inferred only
FBXL18 covaries with ZBTB42ProteinHetionet hetionet:covaries:100128927-80028Inferred only
CALCOCO2 interacts with FBXL18ProteinHetionet hetionet:interacts:10241-80028Inferred only
COPS5 interacts with FBXL18ProteinHetionet hetionet:interacts:10987-80028Inferred only
COPS6 interacts with FBXL18ProteinHetionet hetionet:interacts:10980-80028Inferred only
CUL1 interacts with FBXL18ProteinHetionet hetionet:interacts:80028-8454Inferred only
HSP90AA1 interacts with FBXL18ProteinHetionet hetionet:interacts:3320-80028Inferred only
FBXL18 interacts with KRTAP4-12ProteinHetionet hetionet:interacts:80028-83755Inferred only
MDFI interacts with FBXL18ProteinHetionet hetionet:interacts:4188-80028Inferred only

Show the remaining 16

PLSCR1 interacts with FBXL18ProteinHetionet hetionet:interacts:5359-80028Inferred only
UBC interacts with FBXL18ProteinHetionet hetionet:interacts:7316-80028Inferred only
UBD interacts with FBXL18ProteinHetionet hetionet:interacts:10537-80028Inferred only
FBXL18 participates in Adaptive Immune SystemPathwayReactome R-HSA-1280218Inferred only
FBXL18 participates in Antigen processing: Ubiquitination & Proteasome degradationPathwayReactome R-HSA-983168Inferred only
FBXL18 participates in Cell CyclePathwayReactome R-HSA-1640170Inferred only
FBXL18 participates in Cell Cycle, MitoticPathwayReactome R-HSA-69278Inferred only
FBXL18 participates in Class I MHC mediated antigen processing & presentationPathwayReactome R-HSA-983169Inferred only
FBXL18 participates in FBXL7 down-regulates AURKA during mitotic entry and in early mitosisPathwayReactome R-HSA-8854050Inferred only
FBXL18 participates in G2/M TransitionPathwayReactome R-HSA-69275Inferred only
FBXL18 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
FBXL18 participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
FBXL18 participates in Mitotic G2-G2/M phasesPathwayReactome R-HSA-453274Inferred only
FBXL18 participates in NeddylationPathwayReactome R-HSA-8951664Inferred only
FBXL18 participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
FBXL18 regulates regulation of apoptotic processBiological processgene ontology Q96ME1|GO:0042981Inferred only

Other names

3 names

Resolves to: FBXL18

Also called: F-box and leucine-rich repeat protein 18F-box/LRR-repeat protein 18FBL18

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