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Proteins/UNIPROT:Q8WUP2
Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion..
Function from UniProtKB (Q8WUP2), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
7 statements
7 statements · 3 reference databases · Subject: FBLIM1 · Sources: gene ontology, Hetionet, Reactome
5 names
Resolves to: FBLIM1