Proteins/UNIPROT:Q7Z4H9

FAM220A

ProteinUNIPROT:Q7Z4H9

Promotes dephosphorylation of transcriptional activator STAT3 by interacting with both STAT3 and protein phosphatase PTPN2. This promotes interaction of PTPN2 with STAT3 and mediates STAT3 dephosphorylation by PTPN2, leading to negative regulation of STAT3 transcriptional activator activity. May be required for spermiogenesis or sperm function..

Function from UniProtKB (Q7Z4H9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

22 statements

22 statements · 1 reference database · Subject: FAM220A · Sources: Hetionet

Order

FAM220A covaries with AMZ1ProteinHetionet hetionet:covaries:155185-84792Inferred only
FAM220A covaries with ARHGEF18ProteinHetionet hetionet:covaries:23370-84792Inferred only
BAIAP2L1 covaries with FAM220AProteinHetionet hetionet:covaries:55971-84792Inferred only
FAM220A covaries with BRAT1ProteinHetionet hetionet:covaries:221927-84792Inferred only
CRISPLD2 covaries with FAM220AProteinHetionet hetionet:covaries:83716-84792Inferred only
FAM220A covaries with DIDO1ProteinHetionet hetionet:covaries:11083-84792Inferred only
FAM220A covaries with EHD4ProteinHetionet hetionet:covaries:30844-84792Inferred only
FAM220A covaries with F2RProteinHetionet hetionet:covaries:2149-84792Inferred only
GEMIN8 covaries with FAM220AProteinHetionet hetionet:covaries:54960-84792Inferred only
FAM220A covaries with GPR158ProteinHetionet hetionet:covaries:57512-84792Inferred only
FAM220A covaries with HMCN1ProteinHetionet hetionet:covaries:83872-84792Inferred only
LMTK2 covaries with FAM220AProteinHetionet hetionet:covaries:22853-84792Inferred only

Show the remaining 10

FAM220A covaries with PELP1ProteinHetionet hetionet:covaries:27043-84792Inferred only
PHRF1 covaries with FAM220AProteinHetionet hetionet:covaries:57661-84792Inferred only
FAM220A covaries with PRAM1ProteinHetionet hetionet:covaries:84106-84792Inferred only
FAM220A covaries with RHCGProteinHetionet hetionet:covaries:51458-84792Inferred only
TRPC5OS covaries with FAM220AProteinHetionet hetionet:covaries:100329135-84792Inferred only
XRCC2 covaries with FAM220AProteinHetionet hetionet:covaries:7516-84792Inferred only
FAM220A covaries with ZBTB42ProteinHetionet hetionet:covaries:100128927-84792Inferred only
FAM220A covaries with ZFAND4ProteinHetionet hetionet:covaries:84792-93550Inferred only
FAM220A covaries with ZNF329ProteinHetionet hetionet:covaries:79673-84792Inferred only
ZNF839 covaries with FAM220AProteinHetionet hetionet:covaries:55778-84792Inferred only

Other names

4 names

Resolves to: FAM220A

Also called: C7orf70Protein FAM220ASIPARSTAT3-interacting protein as a repressor

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