Proteins/UNIPROT:Q9BWQ8

FAIM2

ProteinUNIPROT:Q9BWQ8

Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development..

Function from UniProtKB (Q9BWQ8), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

7 statements

7 statements · 2 reference databases · Subject: FAIM2 · Sources: gene ontology, Hetionet

Order

FAS interacts with FAIM2ProteinHetionet hetionet:interacts:23017-355Inferred only
FAIM2 regulates negative regulation of apoptotic processBiological processgene ontology Q9BWQ8|GO:0043066Inferred only
FAIM2 regulates negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsBiological processgene ontology Q9BWQ8|GO:1902042Inferred only
FAIM2 regulates negative regulation of neuron apoptotic processBiological processgene ontology Q9BWQ8|GO:0043524Inferred only
FAIM2 regulates regulation of neuron apoptotic processBiological processgene ontology Q9BWQ8|GO:0043523Inferred only
CDK5 increases the expression of FAIM2ProteinHetionet hetionet:regulates:1020-23017Inferred only
HK1 increases the expression of FAIM2ProteinHetionet hetionet:regulates:3098-23017Inferred only

Other names

8 names

Resolves to: FAIM2

Also called: Fas apoptotic inhibitory molecule 2KIAA0950LFGLFG2Neural membrane protein 35NMP35TMBIM2Transmembrane BAX inhibitor motif-containing protein 2

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