Proteins/UNIPROT:P23610

F8A1; F8A2; F8A3

ProteinUNIPROT:P23610

RAB5A effector molecule that is involved in vesicular trafficking of early endosomes. Mediates the recruitment of HTT by RAB5A onto early endosomes. The HTT-F8A1/F8A2/F8A3-RAB5A complex stimulates early endosomal interaction with actin filaments and inhibits interaction with microtubules, leading to the reduction of endosome motility..

Function from UniProtKB (P23610), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

16 statements

16 statements · 2 reference databases · Subject: F8A1; F8A2; F8A3 · Sources: gene ontology, Hetionet

Order

DNMT3A interacts with F8A1; F8A2; F8A3ProteinHetionet hetionet:interacts:1788-474384Inferred only
DNMT3A interacts with F8A1; F8A2; F8A3ProteinHetionet hetionet:interacts:1788-8263Inferred only
DNMT3A interacts with F8A1; F8A2; F8A3ProteinHetionet hetionet:interacts:1788-474383Inferred only
HTT interacts with F8A1; F8A2; F8A3ProteinHetionet hetionet:interacts:3064-474383Inferred only
HTT interacts with F8A1; F8A2; F8A3ProteinHetionet hetionet:interacts:3064-474384Inferred only
HTT interacts with F8A1; F8A2; F8A3ProteinHetionet hetionet:interacts:3064-8263Inferred only
F8A1; F8A2; F8A3 interacts with SH3GLB1ProteinHetionet hetionet:interacts:51100-8263Inferred only
SH3GLB1 interacts with F8A1; F8A2; F8A3ProteinHetionet hetionet:interacts:474384-51100Inferred only
SH3GLB1 interacts with F8A1; F8A2; F8A3ProteinHetionet hetionet:interacts:474383-51100Inferred only
SNTA1 interacts with F8A1; F8A2; F8A3ProteinHetionet hetionet:interacts:474383-6640Inferred only
SNTA1 interacts with F8A1; F8A2; F8A3ProteinHetionet hetionet:interacts:6640-8263Inferred only
SNTA1 interacts with F8A1; F8A2; F8A3ProteinHetionet hetionet:interacts:474384-6640Inferred only

Show the remaining 4

TLR10 interacts with F8A1; F8A2; F8A3ProteinHetionet hetionet:interacts:474383-81793Inferred only
TLR10 interacts with F8A1; F8A2; F8A3ProteinHetionet hetionet:interacts:474384-81793Inferred only
F8A1; F8A2; F8A3 interacts with TLR10ProteinHetionet hetionet:interacts:81793-8263Inferred only
F8A1; F8A2; F8A3 regulates negative regulation of proteasomal protein catabolic processBiological processgene ontology P23610|GO:1901799Inferred only

Other names

4 names

Resolves to: F8A1; F8A2; F8A3

Also called: ;CpG island proteinFactor VIII intron 22 proteinHAP40

← Every protein Find it in the graph →